Tophus (pi., tophi)

Calculus (stone) or mineral deposit in bone or tissue.


A deposit of solid crystals in the skin or in the joints, especially in someone with gout.


A deposit composed of needlelike crystals of a salt of uric acid that forms a chalky mass on the bones at the joints, most commonly the large joint of the big toe. Tophi result from hyperuricemia, a condition caused by excessive amounts of uric acid in the blood. Hyperuricemia is caused by excess production or decreased excretion of uric acid. Although rare, tophi cause pain and swelling in the affected joint and can destroy the joint and the adjacent bone.


A hard deposit of crystalline uric acid and its salts in the skin, cartilage (especially of the ears), or joints; a feature of gout.


The name given to urate-based deposits which form in connection with joints or tendon sheaths as the result of attacks of gout. At first the tophus is a soft mass, but later becomes quite hard. It is composed of sodium biurate.


A deposit of sodium biurate in tissues near a joint, in the ear, or elsewhere in individuals with gout.


A crystalline accumulation of uric acid compounds commonly observed in cases of gout. Tophi primarily develop in the vicinity of joints and may also appear in the external ear.


Not taken internally but rather applied externally to the body, such as to the skin, eyes, or mouth.


Tophus refers to an accumulation of uric acid crystals that forms in specific tissues, primarily around joints, although occasionally in other areas like the ear. The presence of a tophus indicates hyperuricemia, a condition commonly associated with gout.


A hardened mineral deposit found in the body, often around the joints, consisting of sodium urate accumulations in the skin near a joint, in the ear, or within a bone, typically associated with gout. The term may also be used to describe dental calculus or a nodule related to syphilis.


 


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