The enzymes serum glutamic-oxaloacetic transaminase (SGOT), also known as aspartate aminotransferase, and serum glutamic-pyruvic transaminase (SGPT), also known as alanine amino-transferase. Blood levels of these enzymes are measured to diagnose liver and heart disease.
An enzyme that catalyzes the transfer of an amino group from an amino acid to an a-keto acid in the process of transamination. Examples are glutamic oxaloacetic transaminase (GOT), catalyzing the transamination of glutamate and oxaloacetate to α-ketoglutarate and aspartate, and glutamic pyruvic transaminase (GPT), converting glutamate and pyruvate to a-ketoglutarate and alanine.