Chronic diarrhea in a person who has recently visited a tropical area. In tropical sprue, there are no signs of parasites or other infection. Diarrhea results from malabsorption (impaired absorption of nutrients through the small intestine). Because fat passes through the intestine unabsorbed, stools are bulky and strong smelling. Although the exact cause of tropical sprue remains unknown, in most cases it can be successfully treated with antibiotics.
A disease endemic in Southeast Asia and the Caribbean, marked by diarrhea, nutrient malabsorption, anemia, fatigue, malnutrition, and edema It is similar pathologically to celiac sprue although the involvement of the small intestine is often more extensive. Folate, iron, and vitamin B12 deficiencies are common findings. The administration of folic acid and tetracyclines for 6 to 12 months provides effective treatment.
A condition affecting the small intestine that disrupts the body’s ability to absorb nutrients from food. Predominantly found in India, the Far East, and the Caribbean, sprue is often attributed to an intestinal infection. The symptoms include loss of appetite and weight, mouth inflammation, and fatty diarrhea. The disorder can result in malnutrition and a specific type of anemia known as megaloblastic anemia.
Confirmation of the diagnosis is typically achieved through a jejunal biopsy, which involves taking a tissue sample from the small intestine. Treatment with antibiotics and vitamin and mineral supplements is generally effective in managing the condition.