Tuberculin

A substance which is derived from the culture of the tuberculosis bacillus and is used to test people for the presence of tuberculosis.


A substance derived from tubercle bacilli (tuberculosis- causing organisms), used to diagnose tuberculosis or exposure to the disease.


A protein extract from cultures of tubercle bacilli, used to test whether a person has suffered from or been in contact with tuberculosis. In the Mantoux test a quantity of tuberculin is injected beneath the skin and a patch of inflammation appearing in the next 18-24 hours is regarded as a positive reaction, meaning that a degree of immunity is present.


The name originally given by Koch in 1890 to a preparation derived from the tubercle bacillus Mycobacterium tuberculosis and intended for the diagnosis or treatment of tuberculosis. The basis of the tuberculin reaction is that any person who has been infected with the Mycobacterium tuberculosis, however long ago, has a reaction when a small amount of tuberculin is injected into the skin. A negative reaction means either that the individual has never been infected with the tubercle bacillus, or that the infection has been too recent for sensitivity to have developed. There are various methods of carrying out the test: the Mantoux test is performed by injecting tuberculin into the skin on the forearm. The size of any raised, red area that results is a guide to the extent of possible infection. The Heaf multiple puncture test is also used.


A solution of purified protein derivative of Mycobacterium tuberculosis. It is injected intradermally to determine whether a person has been infected with tuberculosis.


A blend of antigens derived from cultured bacteria responsible for tuberculosis, specifically Mycobacterium tuberculosis.


Substance obtained from the tuberculosis-causing bacteria, utilized in different formulations to diagnose tuberculosis in both children and cattle. When tuberculin is injected into the skin, it does not cause a reaction in a healthy person, but in someone with tuberculosis, it results in an inflammatory response at the site of the injection.


 


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