Category: S
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Shotgun cloning method
A technique for obtaining the desired gene that involves “chopping up” the entire genetic complement of a cell using restriction enzymes, then attaching each (resultant) DNA fragment to a vector and transferring it into a bacterium, and finally screening those (engineered) bacteria to locate the bacteria that are producing the desired product (e.g., a protein).…
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Sexual conjugation
An infrequent occurrence in which two adjacent bacteria stretch out portions of their (cell) membranes to touch one another, fuse; and then pass transposons, jumping genes, or plasmids to each other.
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Sex Chromosomes
Those chromosomes whose content is different in the two sexes of a given species. They are usually labeled X and Y (or W and Z); one sex has XX (or WW), the other sex has XY (or WZ). XX (WW) is female and XY (WZ) is male. The pair of chromosomes that determines the sex…
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Serum Lifetime
The average length of time that a molecule circulates in an organism’s bloodstream before it is cleared from the bloodstream.
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Serotypes
A variety (sub-strain) of a microorganism that is distinguished from others in (strain) via its serological effects (within immune system of the host organism it inhabits). A category of microorganisms or bacteria which have some antigens in common. A series of common antigens which exists in microorganisms and bacteria. A category into which material is…
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Seronegative
Refers to negative results of a serology test. Referring to someone who gives a negative reaction to a serological test. A blood test done for a possible infection that shows a negative result. Producing a negative reaction to serological tests. The term “seronegative” refers to blood serum that has been tested for an infection and…
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Serology
A subdiscipline of immunology, concerned with the properties and reactions of blood sera. It includes the diverse techniques used for the “test tube” measurement of antibody-antigen reactions, including blood typing (e.g., for transfusions). A study of blood serum to measure antibody titers. The study of antigen and antibody reactions in blood serum tests. The scientific…
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Seroconversion
The development of antibodies (specific to that diseasecausing microorganism) in response to vaccination or natural exposure to a disease-causing microorganism. Development of detectable specific antibodies to a disease-causing organism or vaccine. Process where exposure to a pathogen causes a change from negative to a positive finding of antibodies for that pathogen; often observed with tuberculosis.…
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Sequon
A (potential) site on a protein molecule’s “backbone” where a sugar molecule (or a chain of sugar molecules, i.e., an oligosaccharide) may be attached.
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Sequencing (of protein molecules)
The process used to obtain the sequential arrangement of amino acids in a protein molecule.