Facts and Food Sources of Timnodonic acid


Timnodonic acid also called Eicosapentaenoic acid and icosapentaenoic acid, is an omega-3 fatty acid which is given the name 20:5(n-3). In chemical structure, timnodonic acid is a carboxylic acid having 20-carbon chain and 5 cis double bonds.  The first double bond is situated at the third carbon from the omega end. Timnodonic acid is a precursor for various substances which are crucial in human nutrition especially fatty acid docosahexaenoic acid (DHA). It is a precursor for thromboxane-3, prostaglandin-3, and leukotriene-5 eicosanoids. It is both a precursor as well as hydrolytic breakdown product of eicosapentaenoyl ethanolamide.

The diet with high eicosapentaenoic acid reduces serum lipid concentration, prevents platelet aggregation, lowers incidence of cardiovascular disorders and inhibit arachidonic acid conversion into thromboxane-2 and prostaglandin-2 families. The dietary sources of Timnodonic acid are mackerel, herring, salmon, menhaden and sardines.


Food Sources

Food name Weight (g) Timnodonic acid (g)
Fish oil, menhaden 13.6 1.791
Fish, herring, Pacific, dry heat 144 1.788
Fish oil, salmon 13.6 1.771
Fish oil, sardine 13.6 1.379
Fish, herring, Atlantic, cooked, dry heat 143 1.300
Fish, mackerel, salted 80 1.295
Salmon, red (sockeye), smoked 108 0.977
Fish, sablefish, cooked, dry heat 85 0.737
Fish, halibut, greenland, cooked, dry heat 85 0.573
Fish, wolffish, Atlantic, cooked, dry heat 119 0.468
Fish, salmon, coho, wild, cooked, moist heat 85 0.462
Fish, mackerel, spanish, cooked, dry heat 146 0.429
Crustaceans, crab, alaska king, cooked, moist heat 134 0.395
Crustaceans, shrimp, mixed species, canned 128 0.375
Fish oil, cod liver 4.5 0.310
Mollusks, oyster 85 0.300
Crustaceans, spiny lobster 85 0.290
Mollusks, mussel, blue 150 0.282
Fish, bass, striped, cooked, dry heat 124 0.269
Fish, carp, cooked, dry heat 85 0.259



The deficiency of Timnodonic acid causes signs such as chronic pain, fatigue and joint discomfort. It also shows the signs such as hair loss, eczema, dry skin, mood swings and poor circulation.






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